12. Choice A is the correct answer. This is Bullous Pemphigoid. It comes from an interaction of the autoantibody with bullous pemphigoid antigen on the surface of keratinocytes. The bullous lesions come from molecules released from mast cells. Prednisone and azathoprine have been shown to be helpful with this mechanism. Tetracycline has also been shown to be helpful but the mechanism is unknown. Acyclovir is not an accepted treatment regarding this.
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